René of Châlon (November 1519–18 July 1544), also known as Renatus of Châlon, was a Prince of the House of Orange and stadtholder of Holland, Zeeland, Utrecht and Gelre.
He was a son of Count Henry III of Nassau-Breda and Claudia of Chalons-Orange. He was slain in battle in 1544 and succeeded by his cousin William.
